Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01018 |
Dtk Protein, Mouse, Recombinant (mFc)
TK19-2,Tyrosine-protein kinas... |
Mouse | HEK293 Cells |
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144. | |||
TMPJ-01017 |
Dtk Protein, Mouse, Recombinant (hFc)
tyro3,Tyrosine-prote... |
Mouse | HEK293 Cells |
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144. | |||
TMPJ-01081 |
Dtk Protein, Human, Recombinant (His)
RSE,SKY,DTK,Tyrosine-protein ... |
Human | HEK293 Cells |
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th... | |||
TMPK-00407 |
AXL Protein, Human, Recombinant (His & Avi)
AXL oncogene,Axl,EC 2.7.10.1,Tyro7,UFO,ARK,EC 2.7.1... |
Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is e... | |||
TMPK-00472 |
AXL Protein, Cynomolgus, Recombinant (His)
Tyro7,JTK11,AI323647,AXL oncogene... |
Cynomolgus | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Cynomolgus, Recombinant (His) is ex... | |||
TMPJ-00365 |
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
AXLLG,Growth arrest-specific protein 6,AXL rece... |
Human | HEK293 Cells |
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, plat... | |||
TMPK-00410 |
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO,AI3... |
Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec... | |||
TMPK-00408 |
AXL Protein, Human, Recombinant (His & Avi), Biotinylated
AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK1... |
Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio... | |||
TMPJ-01143 |
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
MER,Receptor tyrosine kinase<... |
Human | HEK293 Cells |
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that t... |